Quality Control

Following are the useful Topics, helpful to new as well as experienced professionals in quality improvement of products.  This site is updated on regular basis so visit again and share it.

Bracketing and Matrixing for Stability Testing in Pharmaceuticals

Role and Responsibilities of Quality Control Analyst

Roles, Responsibilities and Job Description of Quality Control Manager

Stand by System Changeover Procedure for Walk in Type Stability Chamber

System Maintenance Procedure for Walk in Type Stability Chamber

IPQC Test for Tablets

What is the RSD Limit for Replicate Standards in HPLC Analysis?

What is LC-MS Analysis?

Qualification of Secondary Reference Standard

Stability Study Protocol

Moisture Vapour Transmission Rate

Particle Size Analysis

Column Restoration Procedures

Causes and Remedy for HPLC Troubleshooting

Guidelines on Stability of Pharmaceutical Products

Can We Use Expired Raw Materials to Manufacture Drug Formulations?

HPLC Column Care and Maintenance

Troubleshooting Problems with Column Backpressure

Troubleshooting Problems with Ghost Peaks

Troubleshooting Problems with Retention Variation

Troubleshooting Problems with Peak Shape

Question and Answer for Quality Control

Question and Answer for In-process Parameters for Tablets and Capsules

Use and Benefits of HPLC Guard Column

Maintenance of Flow Cell

Troubleshooting for UV Detector of HPLC

Troubleshooting for Increased Pressure

GC Troubleshooting Tips

Peak Purity and Peak Identification

What is the Difference Between De-Mineralized Water and Purified Water?

Calculation of System Suitability Parameters

What is the Shelf Life for HPLC Columns?

What is HPLC Column Conditioning? How Long to Equilibrate?

What is the Expiry Date for HPLC Mobile Phase?

Do's and Don'ts : HPLC Analysis

How to Select Buffer in HPLC Method Development?

Troubleshooting: Capillary Electrophoresis

What is % v/v, % w/w and % w/v?

Use of Methanol in KF Titration

What is the Difference between HPLC and HPTLC?

What are Good Chromatography Practices?

What is the Difference between C8 and C18 columns in HPLC?

Chromatographic Calculations

GC Column Change Procedure

Daily and Routine LC Maintenance

Validation of Effectivity of UV Light in Water System

Which Solvent is Better for Chromatography: Methanol or Acetonitrile?

How to Find Impurities in Pharmaceutical Products

Concept of Humidity in Pharmaceutical Industry: Absolute Humidity and

Relative Humidity

Friability Test for Tablets

Particle Size Determination Methods for Tablets Powder

Interview Questions for Quality Control and Quality Assurance

What is Ghost Peaks?

What is the Difference between HPLC and UPLC?

Verification of System Suitability Test

How to make HPLC columns last longer?

Checklist for Preventive Maintenance of HPLC

Troubleshooting Leaks in HPLC

Troubleshooting Abnormal Pressure in HPLC

Troubleshooting Problems with Chromatogram

List of Incompatible Chemicals

Troubleshooting Problems Detected by Smell, Sight or Sound in HPLC

Contract Laboratory Approval Questionnaire

Hold Time Study for Cleaned FBD Bags

Atomic Absorption Spectroscopy

Detergents Used for Cleaning of Pharmaceutical Equipments and Utensils

Understanding of HPLC

Understanding of Gas Chromatography

What is Peak Tailing?

Drifting Retention Times

Troubleshooting Problems with Injector in HPLC

What is Dead Volume and Dwell Volume in HPLC?

Use of UV and Diode-Array (PDA) Detectors in (U)HPLC

Potency Calculation of API in Manufacturing Formula

Prevention of Retention Time Drifts in HPLC Analysis

Why Degassing of HPLC Mobile Phase is Necessary?

Diagnostics Tips and Tricks for Loss of Precision in HPLC

Diagnostics Tips and Tricks for Retention Time in HPLC

Diagnostics Tips and Tricks for System Pressure Problems in HPLC

HPLC Flow Cell Care and Cleaning

Good Laboratory Practice for HPLC

Column Cleaning, Regeneration and Storage of Silica Based Columns

Glassware Cleaning in Laboratory

How to take Baseline in Shimadzu UV-1800 in UV Probe Software?

How to take Spectrum in Shimadzu UV-1800 in UV Probe Software?

Do’s & Don’ts Regarding Operation of Gas Chromatography

Water determination by Karl Fischer Reagent (KF)

Difference between Water Content (Moisture) and Loss on Drying (LOD)

Photostability Study in Pharmaceutical

Difference between Rework and Reprocess

Difference Between Assay and Potency

Difference between Assay and Purity

A Forced Degradation Study (Stress Testing)

Types of Dissolution Test Apparatus

Types of HPLC Detectors

Concept and Difference Between mg & IU

Oral Dispersible Tablets

General HPLC Column Care

Troubleshooting Guide – HPLC

Good Laboratory Practice

Tablet Friability Test Specification