The "Handbook of Pharmaceutical Excipients Sixth Edition" is a comprehensive guidebook providing in-depth information on more than 400 pharmaceutical excipients commonly used in drug formulation. This handbook is an essential reference tool for pharmacists, pharmaceutical scientists, and formulation experts who need to understand the properties and functions of excipients in drug formulations.
The sixth edition of the "Handbook of Pharmaceutical Excipients" has been updated to include the latest information on excipient development and usage. The handbook contains detailed monographs on each excipient, covering its chemical and physical properties, pharmaceutical applications, and regulatory status.
The guidebook is divided into two sections: the first gives a broad review of excipients and their roles in pharmaceutical formulations, and the second offers particular monographs on each excipient. Each monograph offers a full explanation of the excipient, its features, applications, and any regulatory information that may be applicable. The handbook's general overview section gives a thorough introduction to excipients and their roles in pharmaceutical formulations. This section discusses the many types of excipients, their regulatory status, and their roles in medication formulation. It also offers information on excipient safety and toxicity, as well as advice for selecting excipients depending on their intended usage.
The individual monographs in the handbook cover over 400 pharmaceutical excipients, including both commonly used excipients and newer, less well-known excipients. Each monograph provides detailed information on the chemical and physical properties of the excipient, including its molecular weight, solubility, and melting point. It also describes the excipient's pharmaceutical applications, including its uses as a binder, diluent, lubricant, or other functional roles in drug formulation.
The handbook's monographs also offer information on the regulatory status of each excipient. This data is critical for pharmaceutical scientists and formulators who must guarantee that their formulations fulfill regulatory criteria. The regulatory information includes the excipient's status with regulatory organizations such as the FDA and the European Medicines Agency (EMA), as well as any relevant safety or toxicity data.
The breadth and depth of information provided on each excipient is one of the "Handbook of Pharmaceutical Excipients"' strengths. Each monograph contains thorough information on the physical and chemical features of the excipient, as well as its medicinal uses and regulatory status. This makes it an indispensable resource for pharmaceutical scientists and formulators who need to choose the best excipients for their medication formulations.
The "Handbook of Pharmaceutical Excipients" provides important appendices that provide extra information on excipient-related subjects in addition to its thorough treatment of excipients. For example, the handbook contains an appendix on the use of excipients in pediatric formulations, which gives recommendations on selecting safe and effective excipients for use in children.
The handbook also includes an appendix on excipient compatibility, which provides guidance on selecting excipients that are compatible with each other in drug formulations. This is an important consideration for formulators, as incompatible excipients can lead to formulation problems such as precipitation or instability.
Overall, the "Handbook of Pharmaceutical Excipients Sixth Edition" is a valuable resource for anybody interested in medication formulation or pharmaceutical research. It is an important resource for pharmaceutical scientists, formulators, and regulators due to its thorough coverage of excipients, as well as its relevant appendices and regulatory information. Whether you require information on a specific excipient or advice on selecting excipients for a novel medicine formulation, the "Handbook of Pharmaceutical Excipients" is a must-have resource.
Handbook of Pharmaceutical Excipients Sixth Edition
The Handbook of Pharmaceutical Excipients collects together essential data on the physical properties of excipients as well as provides information on their safe use and applications. All 400+ monographs are also thoroughly cross-referenced and indexed to allow their identification by chemical, non-proprietary or trade names. It is internationally recognized as the authoritative source of information on pharmaceutical excipients and a comprehensive guide to uses, properties and safety.
Monographs benefit from a standardized, easy-to-use template and include:
- Pharmacopeial information from the UK, Europe, Japan and the United States where relevant
- Non-proprietary names and synonyms
- Chemical name, CAS Registry number, empirical formula, molecular weight
- Functional categories, applications and incompatibilities
- Material description and typical properties
- Safety, stability, storage and handling of information
- Method of manufacture
- Related substances
- Primary references
- Editorial comments
- Author's details and revision date
Changes to this new edition:
- Contains revised and updated monographs
- 20 + new monographs including amino acids Arginine, Proline and Asparagine
- Includes newly added Raman spectra for many excipients
- New chapter content including information on excipients in oral solid dose formulations, and pediatric formulations
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